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Baggio–Yoshinari syndrome
The Baggio–Yoshinari syndrome (BYS), formerly known as the Brazilian Lyme-like disease and Brazilian human borreliosis, is a disease transmitted by the ''Amblyomma cajennense'' tick, but the organism that causes the infection is still unknown.〔 Clinical features resemble those of Lyme disease (LD).〔
== History ==
In 1989, Brazilian researchers Professors Domingos Baggio (an entomologist from the Biomedical Sciences Institute of the University of São Paulo), Paulo Yasuda (a microbiologist from the same institute) and Natalino Hajime Yoshinari (a physician from the Rheumatology Department at University of São Paulo's Medical School〔) started research on Lyme disease in Brazil, by suggestion of Dr. Allen Steere. At that time, LD was almost unknown among Brazilian physicians.〔Revista Brasileira de Pesquisas Médicas e Biológicas vol.40 no.4 Ribeirão Preto Apr. 2007: (Description of Lyme disease-like syndrome in Brazil. Is it a new tick borne disease or Lyme disease variation? )〕
The first cases were described in Brazil in 1992 in siblings from Cotia, São Paulo that developed symptoms as erythema migrans, general flu-like symptoms and arthritis after being bitten by ticks. Although the symptoms were similar to those presented by patients of Lyme disease, clinical and laboratorial results were considerably different. Ticks of the ''Ixodes ricinus'' complex were not found at the risk areas; bacteria from the ''Borrelia burgdorferi sensu lato'' complex were not isolated in biological fluids and tissues whatsoever.〔 Blood analysis of patients on electron microscopy exhibited structures resembling spirochaete-like microorganisms. For these reasons, the Brazilian zoonosis was named Baggio–Yoshinari Syndrome (BYS) and defined as:
:"Exotic and emerging Brazilian infectious disease, transmitted by ticks not belonging to the ''Ixodes ricinus'' complex, caused by latent spirochetes with atypical morphology, which originates LD-like symptoms, except for occurrence of relapsing episodes and auto-immune disorders".〔Revista da Associação Médica Brasileira vol.56 no.3 São Paulo, 2010: (Brazilian Lyme-like disease or Baggio-Yoshinari syndrome: exotic and emerging Brazilian tick-borne zoonosis )〕
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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